Light Yellow Liquid 4- Methylpropiophenone CAS 5337-93-9

  • Light Yellow Liquid 4- Methylpropiophenone CAS 5337-93-9
  • Light Yellow Liquid 4- Methylpropiophenone CAS 5337-93-9
  • Light Yellow Liquid 4- Methylpropiophenone CAS 5337-93-9
  • Light Yellow Liquid 4- Methylpropiophenone CAS 5337-93-9
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Light Yellow Liquid 4- Methylpropiophenone CAS 5337-93-9
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4'-Methylpropiophenone Chemical Properties
Melting point 7.2 °C
Boiling point 238-239 °C(lit.)
density 0.993 g/mL at 25 °C(lit.)
refractive index n20/D 1.528(lit.)
Fp 229 °F
storage temp. Inert atmosphere,Room Temperature
solubility Soluble in chloroform and hexane.
form Oil
color Colourless
Specific Gravity0.99
BRN 2042137
CAS DataBase Reference5337-93-9(CAS DataBase Reference)
NIST Chemistry Reference4'-Methylpropiophenone(5337-93-9)
4'-Methylpropiophenone Usage And Synthesis
Chemical Propertiesclear light yellow liquid
Uses4'-methylpropiophenone has been reported to be used in the synthesis of pharmaceutical compounds such as tolperisone and other muscle relaxants. The substance is also a starting material in the synthesis of 4-methylmethcathinone (mephedrone). Mephedrone has been encountered as a ‘legal high’ and on the illicit drug market masquerading as cocaine (in powder form), MDMA (in tablet form) and as an adulterant. According to the 2016 European Drugs Market Report produced by the European Monitoring Centre for Drugs and Drug Addiction (EMCDDA), mephedrone has created a specific demand and carved its own distinct market share.
Uses4′-Methylpropiophenone is a chemical reagent used in electrocarboxylation reactions.
Application4′-Methylpropiophenone can be used as a building block to synthesize:
N-(4-Chlorophenyl)-N′-[1-(4-methylphenyl)propyl]urea as a potential CRAC channel inhibitor.
Mono and trinuclear cobaloxime/organocobaloxime complexes, which are used as efficient catalysts for the synthesis of cyclic carbonates.
Tolperisone (TOL) via acid-catalyzed reaction with piperidine hydrochloride and 1,2-dioxolane.
DefinitionChEBI: 4-methylpropiophenone is an aromatic ketone that is propiophenone bearing a methyl group at C-4. It derives from a propiophenone.
Product Name:4'-Methylpropiophenone
Synonyms:P-TOLYL ETHYL KETONE;4'-METHYLPROPIOPHENONE;Ethylp-tolylketone;p-Propionyltoluene;Propiophenone, 4'-methyl-;1-Propanone, 1-(4-methylphenyl)-;4-Toluylethane;4'-METHYLPROPIOPHENONE, TECH, 90%
Product Categories:C10;Carbonyl Compounds;Ketones;Aromatic Propiophenones (substituted);Carbonyl Compounds;Intermediate;5337-93-9
Mol File:5337-93-9.mol
CAS 5337-93-9

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